{"id":54,"date":"2019-08-08T12:49:40","date_gmt":"2019-08-08T12:49:40","guid":{"rendered":"http:\/\/www.cironpharma.com\/blog\/?p=54"},"modified":"2019-09-25T06:59:35","modified_gmt":"2019-09-25T06:59:35","slug":"behind-pharma-doors-how-formulations-are-made","status":"publish","type":"post","link":"https:\/\/www.cironpharma.com\/blog\/behind-pharma-doors-how-formulations-are-made\/","title":{"rendered":"Behind Pharma Doors &#8211; How Formulations are Made"},"content":{"rendered":"\n<p>Pharmaceutical formulations are\nmade through a process in which different chemical substances, including active\ningredients and few selected inactive ingredients are combined to produce a\npharmaceutical drug.<\/p>\n\n\n\n<p><strong>Active Pharmaceutical Ingredient (API) and Inactive\nIngredients<\/strong><\/p>\n\n\n\n<p>Active\nPharmaceutical Ingredient (API) is a term used to refer to the chemically\nactive components in a pharmaceutical drug. Example of pharmaceutical drugs: tablet,\ncapsule, cough syrup, etc. API is the central ingredient in a drug; while the inactive\ningredients in it are known as excipients. For example, the acetaminophen in a\npain relief tablet is its API; whereas, lactose, glucose, cellulose and the\nrest are its excipients.<\/p>\n\n\n\n<p><strong>Importance of API in Pharmaceutical Formulations\n<\/strong><\/p>\n\n\n\n<p>The purpose of\nAPIs according to FDAis to cause\npharmacological activity or other direct effects in care and treatment of\ndiseases. Both prescription and over-the-counter drugs by <strong><a href=\"http:\/\/www.cironpharma.com\/profile.asp\">formulation companies\nin India<\/a><\/strong> are a mixture of APIs and excipients.&nbsp; <\/p>\n\n\n\n<p><strong>Types of Pharmaceutical Formulations:<\/strong><\/p>\n\n\n\n<p>Let\u2019s have a\nlook at the different types of pharmaceutical formulations from <strong><a href=\"http:\/\/www.cironpharma.com\/products.asp\">manufacturer of pharmaceutical\nproducts<\/a>. <\/strong><\/p>\n\n\n\n<ul><li><strong>Tablets:<\/strong> Immediate-release tablets, sustained-release tablets, delayed-release tablets and film-coated tablets<\/li><\/ul>\n\n\n\n<ul><li><strong>Capsules: <\/strong>Powdered and granule filling capsules<\/li><\/ul>\n\n\n\n<ul><li><strong>Pellets: <\/strong>Capsule-filled pellets<\/li><\/ul>\n\n\n\n<ul><li><strong>Powders: <\/strong>FDA approved powders<\/li><\/ul>\n\n\n\n<ul><li><strong>Oral and Parenteral Liquids: <\/strong>Solutions, Suspensions, Emulsions<\/li><\/ul>\n\n\n\n<ul><li><strong>Semi-solids: <\/strong>Creams, Ointments, Gels, Lotions<\/li><\/ul>\n\n\n\n<p><strong>What are the three major considerations to be studied\nduring formulation development?<\/strong><\/p>\n\n\n\n<ul><li>Formulation of pharmaceutical drugs is well within the FDA guidelines <\/li><li>Proper protection\nof drug formulations from humidity and various external factors<\/li><li>Whether the\nbitter or salty odor of drug substances are properly masked or not; for example:\ncoated capsules, sweet syrups <\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Pharmaceutical formulations are made through a process in which different chemical substances, including active ingredients and few selected inactive ingredients are combined to produce a pharmaceutical drug. Active Pharmaceutical Ingredient (API) and Inactive Ingredients Active Pharmaceutical Ingredient (API) is a term used to refer to the chemically active components in a pharmaceutical drug. Example of<\/p>\n","protected":false},"author":1,"featured_media":55,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[5,6,4],"_links":{"self":[{"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/posts\/54"}],"collection":[{"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/comments?post=54"}],"version-history":[{"count":2,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/posts\/54\/revisions"}],"predecessor-version":[{"id":57,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/posts\/54\/revisions\/57"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/media\/55"}],"wp:attachment":[{"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/media?parent=54"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/categories?post=54"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cironpharma.com\/blog\/wp-json\/wp\/v2\/tags?post=54"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}