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Active Pharmacutical Ingradiants
Active Pharmacutical Ingradiants
  Lyophilized products
  Lyophilized products are rarely manufactured in India belonging to a niche field. Lyophilization is a dehydration process typically used to preserve a perishable material and increase the shelf life of some pharmaceuticals for many years.

Lyophilization has been used to stabilize many types of chemical components used in IVDs. In their liquid form, many such biochemical and chemical reagents are unstable, biologically and chemically active, temperature sensitive, and chemically reactive with one another. Because of these characteristics, the chemicals may have a very short shelf life, may need to be refrigerated, or may degrade unless stabilized. When performed properly, the process of Lyophilization solves these problems by putting reagents into a state of suspended activity.

Lyophilized works by freezing the material and then reducing the surrounding pressure and adding enough heat to allow the frozen water in the material to sublime directly from the solid phase to the gas phase. At Ciron, we use Lyophilized products to increase the shelf life of our pharmaceutical formulations. By removing the water from the material and sealing the material in a vial, the material can be easily stored, shipped, and later reconstituted to its original form for injection or vaccines.

Sealed Lyophilized products prevent the reabsorption of moisture, thus, it can be stored at room temperature without refrigeration, and be protected against spoilage for many years. Preservation is possible because the greatly reduced water content inhibits the action of microorganisms and enzymes that would normally spoil or degrade the substance.

Ciron manufactures Lyophilized products, comprising in its widest range of formulations with an independent, state-of-the-art manufacturing facility. Following are Lyophilized products.
Sr. Generic Name Dosage Form Therapeutic Category
1 Aceclofenac Injection 150mg Lyophillized Injection NSAID
2 Aciclovir for Injection USP 250mg/vial & 500mg/vial Lyophillized Injection Antiviral
3 Amphotericin-B for Injection USP 50mg/vial & 100mg/vial Lyophillized Injection Antifungal antibiotic
4 Azithromycin for Injection 500mg/vial Lyophillized Injection Antibacterial antibiotic
5 Dobutamine for Injection USP 250mg/vial Lyophillized Injection Cardiac Tonic
6 Esomeprazole Sodium Powder for Injection 40mg/vial Lyophillized Injection Proton pump inhibitor
7 Famotidine Injection 20mg/vial & 40mg/vial Lyophillized Injection Anti-ulcer
8 Lansoprzole for Injection 30mg/vial Lyophillized Injection Proton pump inhibitor
9 Prednisolone Sodium Phosphate Injection USP 30mg/ml Injection Corticosteroid
10 Methylprednisolone Sodium Succinate for Injection USP 40mg/vial,80mg/vial, 125mg/vial, 500mg/vial, 1gm/vial Powder/Lyophillized Injection Glucocorticoid
11 Nicorandil for Injection 2mg/vial & 48mg/vial Lyophillized Injection Antibiotic agent
12 Omeprazole for injection 40mg/vial Lyophillized Injection Proton pump inhibitor
13 Pantoprazole for Injection 40mg/vial Lyophillized Injection Proton pump inhibitor
14 Pralidoxime Chloride for Injection USP 1mg/vial Lyophillized Injection Antidote for nervine poisioning
15 R-Ondansetron Injection 2mg/ml Injection Anti-emetic
16 Rabeprazole Sodium for Injection 20mg/vial Lyophillized Injection Proton pump inhibitor
17 Rifampicin for Injection 600mg/vial Lyophillized Injection Bactericidal
18 Ropivacaine Injection 2mg/ml, 5mg/ml, 7.5mg/ml & 10mg/ml Injection Local anaesthetic
19 S-Bupivacaine Injection 2.5mg/ml, 5mg/ml,  7.5mg/ml Injection Surgical anaesthetic
20 S-Ketamine Injection 5mg/ml & 25mg/ml Injection General anaesthetic
21 Succinylcholine Chloride Injection USP 100mg/vial, 500mg/vial Powder/Lyophillized Injection Neuromuscular blocking agent
22 Vancomycin Hydrochloride Sterile USP 500mg/vial, 1gm/vial Lyophillized Injection Antibiotic antibacterial
23 Vecuronium Bromide for Injection 4mg/vial & 10mg/vial Lyophillized Injection Neuromuscular blocking agent
24 Voriconazole for Injection 20mg/vial Lyophillized Injection Antifungal
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